Plasma exchange calculator

Please answer ALL the following questions.

1. What is the patient's sex?

Male
Female

2. What is the patient's weight in kilograms?

3. How many plasma volumes do you want to exchange?

0.8
1.0
1.5
2.0
Others

Please specify how many plasma volumes you want to exchange:

4. What is the patient's latest haematocrit (in percentage, e.g. 45%)?

5. What is the patient's body habitus?

Normal
Thin
Fat
Muscular

6. Is the latest albumin < 35 g/L or ≥ 35 g/L?

< 35 g/L
≥ 35 g/L

7. Are any of the following conditions present? Check all that apply.

The current plasma exchange cycle is the 4th, that is following within a week of the 1st.
Or equivalently, an 8th cycle within a week of the 5th, a 12th cycle within a week of the 9th, etc

Patient has pre-existing thrombocytopenia or coagulopathy, and is currently undergoing frequent plasma exchange cycles

PT > 21.2 seconds (i.e. >1.8 x the upper limit of normal)

APTT > 58.0 seconds (i.e. > 1.8 x the upper limit of normal)

Fibrinogen < 1.0 g/L

Ongoing bleeding

Method of calculation	Volume of normal saline / mL	Volume of 5% albumin / mL	Volume of FFP / mL
Gilcher's rule of 5, limiting normal saline to 500 mL or less under any circumstances (RECOMMENDED)
Gilcher's rule of 5, allowing normal saline to exceed 500 mL if albumin ≥ 35 g/L
Simplified rule of thumb for calculating patient's plasma volume, limiting normal saline to 500 mL or less under any circumstances
Simplified rule of thumb for calculating patient's plasma volume, allowing normal saline to exceed 500 mL if albumin ≥ 35 g/L